Table 5.
Comparison of clinical and laboratory variables based on age.
| Age < 65 (n = 848) | Age ≥ 65 (n = 220) | p-value | |
|---|---|---|---|
| Age | 52 (45–58) | 69 (67–72) | |
| Male, n | 441 (52) | 107 (48.6) | 0.373 |
| AST, IU/L | 33 (25–51.75) | 32 (25–46.75) | 0.49 |
| ALT, IU/L | 25 (17–43) | 21 (14–29) | < 0.001* |
| Platelet, (× 109/L) | 210.5 (165–254.75) | 182 (151–228) | < 0.001* |
| GGT, IU/L | 47 (23–103) | 39 (23–73) | 0.033* |
| FIB-4 | 1.6 (1.1–2.55) | 2.93 (2.02–4) | < 0.001* |
| APRI | 0.41 (0.29–0.7) | 0.46 (0.33–0.73) | 0.097 |
| AST/ALT | 1.28 (0.91–1.81) | 1.62 (1.15–2.38) | < 0.001* |
| MRE, kPa | 2.42 (2.01–3.3) | 2.73 (2.16–3.88) | < 0.001* |
| Advanced fibrosis, n | 146 (17.2) | 52 (23.6) | 0.029* |
Data are presented as median with interquartile range in parentheses, or numbers of subjects with percentage in parentheses. AST aspartate aminotransferase, ALT alanine aminotransferase, GGT gamma-glutamyl transferase, kPa kilopascals, *are the parameters with p < 0.05.