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. 2021 Jun 30;11:13575. doi: 10.1038/s41598-021-92963-w

Table 1.

Baseline characteristics stratified by depression-related weight change in Ontario adults in the NPHS 1996, CCHS Cycle 1.1, CCHS Cycle 2.1 (n = 59,315).

Depressive episodes with weight change No depressive episodes
Weight gain No weight change Weight loss No depressive episodes
N 562 2530 873 55,350
Age group % (95% CI)
 18–24 16.8 (10.3–23.2) 18.3 (16.1–20.5) 19.2 (15.0–23.4) 12.6 (12.2–13.1)
 25–34 22.0 (17.3–26.7) 22.3 (19.9–24.7) 20.4 (16.4–24.3) 18.7 (18.2–19.3)
 35–44 30.5 (25.1–35.9) 27.9 (25.4–30.3) 27.6 (23.3–31.9) 24.0 (23.5–24.6)
 45–54 20.4 (15.9–25.0) 19.5 (17.3–21.7) 18.0 (13.9–22.1) 18.4 (17.9–18.9)
 55–64 7.6 (4.5–10.8) 7.7 (6.4–9.0) 7.3 (4.2–10.4) 11.8 (11.5–12.2)
 65+ 2.7 (0.3–5.0) 4.3 (3.4–5.3) 7.5 (5.0–10.0) 14.3 (14.0–14.7)
Sex  % (95% CI)
 Female 73.2 (67.2–79.3) 68.7 (66.1–71.3) 57.5 (52.4–62.7) 50.4 (49.8–51.1)
 Male 26.8 (20.7–32.8) 31.3 (28.7–33.9) 42.5 (37.3–47.6) 49.6 (48.9–50.2)
Education level % (95% CI)
 Less than high school 17.0 (12.8–21.3) 19.9 (17.6–22.2) 21.6 (17.2–26.0) 17.4 (17.0–17.9)
 High school graduate 23.0 (17.2–28.8) 20.8 (18.6–23.0) 21.8 (17.8–25.9) 21.5 (21.0–22.0)
 Post-secondary 60.0 (53.7–66.2) 59.3 (56.6–62.0) 56.6 (51.5–61.6) 61.1 (60.5–61.7)
Annual household income % (95% CI)
 < $20,000 16.6 (12.1–21.1) 16.8 (14.7–19.0) 19.4 (15.8–23.1) 10.9 (10.5–11.3)
 $20,000–80,000 60.6 (54.3–66.9) 59.7 (56.6–62.8) 57.2 (51.8–62.6) 60.4 (59.8–61.1)
 > $80,000 22.8 (17.3–28.3) 23.4 (20.7–26.2) 23.4 (18.4–28.4) 28.7 (28.1–29.3)
Marital status % (95% CI)
 Married or common-law 52.5 (46.1–58.8) 50.2 (47.5–53.0) 42.6 (37.5–47.7) 65.1 (64.5–65.7)
 Single, separated, divorced, or widowed 47.5 (41.2–53.9) 49.8 (47.0–52.5) 57.4 (52.3–62.5) 34.9 (34.3–35.5)
Geography % (95% CI)
 Urban 85.2 (81.5–88.9) 90.4 (89.0–91.7) 87.2 (84.3–90.1) 86.8 (86.4–87.1)
 Rural 14.8 (11.1–18.5) 9.6 (8.3–11.0) 12.8 (9.9–15.7) 13.2 (12.9–13.6)
Ethnicity % (95% CI)
 White 90.9 (87.1–94.7) 86.4 (84.1–88.7) 85.9 (81.4–90.5) 83.4 (82.8–83.9)
 Other 9.1 (5.3–12.9) 13.6 (11.3–15.9) 14.1 (9.5–18.6) 16.6 (16.1–17.2)
Born in Canada % (95% CI)
 Born in Canada 79.0 (73.4–84.6) 75.3 (72.6–78.0) 77.9 (73.1–82.7) 69.3 (68.6–69.9)
 Born outside of Canada 21.0 (15.4–26.6) 24.7 (22.0–27.4) 22.1 (17.3–26.9) 30.7 (30.1–31.4)
Smoking status % (95% CI)
 Current 39.6 (33.3–45.9) 40.5 (37.8–43.1) 47.7 (42.7–52.8) 25.3 (24.7–25.8)
 Former 35.6 (29.6–41.6) 31.4 (28.9–33.9) 30.1 (25.1–35.1) 35.7 (35.1–36.3)
 Never 24.8 (19.7–30.0) 28.1 (25.5–30.7) 22.2 (17.6–26.8) 39.0 (38.4–39.6)
Alcohol consumption % (95% CI)
 Frequent 56.4 (50.3–62.5) 59.9 (57.2–62.6) 57.7 (52.6–62.8) 62.8 (62.2–63.4)
 Occasional 23.1 (18.1–28.1) 23.5 (21.1–25.8) 20.2 (16.4–24.0) 18.4 (17.9–18.9)
 Former 15.8 (11.6–20.0) 10.8 (9.3–12.4) 15.9 (12.1–19.7) 10.7 (10.4–11.1)
 Abstain 4.7 (2.4–6.9) 5.8 (4.1–7.5) 6.2 (2.7–9.7) 8.1 (7.7–8.5)
Physical activity level % (95% CI)
 Active 17.6 (13.1–22.1) 21.4 (19.1–23.7) 23.2 (18.9–27.4) 21.5 (21.0–22.0)
 Moderate 26.0 (20.1–31.9) 22.4 (20.2–24.6) 21.2 (17.2–25.2) 24.0 (23.5–24.5)
 Inactive 56.4 (50.1–62.7) 56.2 (53.5–58.9) 55.6 (50.6–60.7) 54.5 (53.9–55.2)
High blood pressure % (95% CI)
 Yes 13.6 (8.6–18.7) 9.4 (7.9–10.9) 10.9 (7.6–14.2) 12.3 (12.0–12.7)
 No 86.4 (81.3–91.4) 90.6 (89.1–92.1) 89.1 (85.8–92.4) 87.7 (87.3–88.0)
Heart disease % (95% CI)
 Yes 2.5 (1.3–3.7) 4.8 (3.8–5.9) 6.5 (2.9–10.2) 4.3 (4.1–4.5)
 No 97.5 (96.3–98.7) 95.2 (94.1–96.2) 93.5 (89.8–97.1) 95.7 (95.5–95.9)
BMI category % (95% CI)a
 Under 25 kg/m2 26.2 (20.1–32.2) 47.8 (45.0–50.6) 57.9 (52.9–62.9) 42.4 (41.8–43.0)
 25–30 kg/m2 36.4 (30.3–42.6) 31.9 (29.3–34.6) 29.0 (24.5–33.4) 38.5 (37.9–39.1)
 30 kg/m2 and above 37.4 (31.5–43.4) 20.3 (18.1–22.4) 13.2 (9.7–16.6) 19.2 (18.7–19.6)
Antidepressant use % (95% CI)b
 Yes 43.7 (36.2–51.1) 23.8 (21.0–26.6) 29.2 (24.0–34.4) 2.9 (2.7–3.1)
 No 56.3 (48.9–63.8) 76.2 (73.4–79.0) 70.8 (65.6–76.0) 97.1 (96.9–97.3)
Medication for blood pressure % (95% CI)b
 Yes 6.6 (3.6–9.6) 6.6 (4.9–8.2) 8.5 (4.8–12.2) 10.3 (9.9–10.7)
 No 93.4 (90.4–96.4) 93.4 (91.8–95.1) 91.5 (87.8–95.2) 89.7 (89.3–90.1)
Medication for heart problems % (95% CI)b
 Yes 3.8 (1.2–6.3) 3.7 (2.5–4.9) 5.4 (1.4–9.5) 4.4 (4.2–4.7)
 No 96.2 (93.7–98.8) 96.3 (95.1–97.5) 94.6 (90.5–98.6) 95.6 (95.3–95.8)

Weighted using survey weights provided by Statistics Canada; all missing covariates imputed.

aBMI categories corrected using Gorber’s correction equations.

bN = 39,717, excluding participants not asked optional medication module (n = 19,552) or missing information on medication (n = 45).