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. 2021 Jun 30;11:13575. doi: 10.1038/s41598-021-92963-w

Table 3.

Multivariable adjusted hazard models for depression-related weight change and incident type 2 diabetes for Ontario adults in the NPHS 1996, CCHS Cycle 1.1, CCHS Cycle 2.1 (n = 59,315).

Depressive episodes Total population Men Women
HR adjusted for age and sex (95% CI) HR fully-adjusteda (95% CI) HR adjusted for age (95% CI) HR fully-adjusteda (95% CI) HR adjusted for age (95% CI) HR fully-adjusteda (95% CI)
Depression-related weight gain versus no depression 1.79 (1.39–2.31) 1.70 (1.32–2.20) 1.57 (0.93–2.65) 1.46 (0.86–2.47) 1.89 (1.43–2.51) 1.82 (1.38–2.41)
Depression with no weight change versus no depression 1.30 (1.10–1.52) 1.23 (1.04–1.45) 1.29 (0.99–1.68) 1.20 (0.92–1.56) 1.30 (1.06–1.59) 1.24 (1.01–1.53)
Depression-related weight loss versus no depression 1.20 (0.87–1.65) 1.05 (0.77–1.43) 1.55 (1.01–2.37) 1.34 (0.87–2.09) 0.91 (0.56–1.49) 0.81 (0.52–1.26)
Depression-related weight gain versus weight loss 1.50 (1.00–2.24) 1.62 (1.09–2.42) 1.02 (0.52–1.99) 1.09 (0.55–2.15) 2.07 (1.18–3.63) 2.26 (1.34–3.81)
Depression-related weight gain versus no weight change 1.38 (1.03–1.86) 1.39 (1.03–1.86) 1.22 (0.68–2.18) 1.22 (0.68–2.18) 1.46 (1.04–2.05) 1.47 (1.04–2.06)
Depression with no weight change versus weight loss 1.08 (0.76–1.54) 1.17 (0.83–1.66) 0.83 (0.51–1.37) 0.89 (0.54–1.48) 1.42 (0.84–2.40) 1.54 (0.95–2.51)

Weighted using survey weights provided by Statistics Canada; all missing covariates imputed.

aEstimates adjusted for age categories, sex, education, income, marital status, geography, born in Canada, ethnicity, smoking, alcohol consumption, physical activity levels, self-reported hypertension and heart disease, and survey cycle.