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Ang2 regulates glucose-responsive insulin secretion through dynamic F-actin remodeling. Representative micrographs of F-actin organization in insulin-secreting cells at (a) 2 mM and (b) 20 mM glucose challenge. White arrowheads indicate thick and highly polymerized F-actin. Yellow arrowheads indicate depolymerized F-actin. Scale bars: 50 µm.
