Fig. 2.

Effect of Dvd treatment on effector molecules and inhibitory receptors in eNKs. A Representative flow cytometry plots showing the expression of IFN-γ, granzyme-B, perforin, TRAIL, FasL, and NKG2A in eNKs. eNKs were harvested on day 14 and treated with Dvd or Dara for 12 h. B Significantly increased expression of IFN-γ and perforin and decreased expression of NKG2A was observed with eNKs administered in combination with Dvd compared with all other treatments (mean ± standard deviation (SD); n = 5). *p < 0.05, **p < 0.001, and ***p < 0.0001