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. 2021 Jun 17;42:1604061. doi: 10.3389/phrs.2021.1604061

TABLE 5.

Summary of potential therapeutic drugs for COVID-19.

Intervention Type Mechanisms References
Remdesivir Antiviral Remdesivir interferes with virus RNA polymerases to inhibit virus [120, 129]
Lopinavir/ritonavir Antiviral Inhibits 3CL protease activity, blockage of protein processing [123]
Favipiravir Antiviral Inhibits viral RNA polymerase, thus interfering with viral replication [137]
Hydroxychloroquine/Chloroquine Antiviral/Antimalaria Endosomal acidification fusion inhibitor anti-inflammatory activity [129]
Convalescent plasma Antiviral Convalescent plasma from cured patients provides a protective antibody against SARS-CoV-2 [144]
Tocilizumab mAb Interleukin-6 inhibitor, humanized mAb targeting IL-6, immunosuppressive, blockage of a cytokine storm [151, 152]
Bevacizumab mAb Humanized mAb targeting VEGF [154]