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. 2021 Jun 17;12:658374. doi: 10.3389/fmicb.2021.658374

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Copyright © 2021 Kortright, Doss-Gollin, Chan and Turner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Competition assays in LB media (black) and M9 media (blue) showed that E. coli mutants resistant to phage T6 (A), phage U115 (B), or albicidin (C) did not measurably differ in fitness, relative to a non-resistant wild-type strain. Each point represents results from independent competition assays (n = 3), and statistical significance was determined using a t-test comparing competitive index of the resistant mutant relative to the competitive index of BW25113ΔicdC. None of the competitive indexes of the resistant mutants were statistically significant in LB media. Competitive indexes of resistant mutants that were statistically significant in M9 media are indicated with * (P < 0.05, unpaired t-test).