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. 2021 Jun 17;12:658374. doi: 10.3389/fmicb.2021.658374

TABLE 1.

Putative resistance mutations in the tsx gene, for each E. coli mutant selected for spontaneous resistance to either phage T6, phage U115, or albicidin.

Strains Mutation type Alteration in tsx Alteration in Tsx
T6 R1 Deletion deletion of 291-321 E79Stop
T6 R2 Insertional Element IS2 at -75 promoter region
T6 R3 Deletion deletion of 402-733
T6 R4 Nonsense G773A * W236Stop
T6 R5 Insertional Element IS2 at 403
T6 R6 Nonsense G435A W124Stop
T6 R7 Insertional Element IS2 at 165 IS2
T6 R8 Missense T725G * L220R
T6 R9 Nonsense G535T E157Stop
T6 R10 Deletion deletion of 410-420 * R146Stop
U115 R1 Insertional Element IS3 at 400
U115 R2 Insertion insertion (1bp) at 53 signal peptide; E24Stop
U115 R3 Insertional Element IS1 at 774
U115 R4 Nonsense G773A * W236Stop
U115 R5 Missense T31A signal peptide; V11E
U115 R6 Insertional Element IS2 at 161
U115 R7 Nonsense C375G Y103Stop
U115 R8 Missense T725G * L220R
U115 R9 Deletion deletion of 429-435 L135Stop
U115 R10 Deletion deletion of 410-420 * R146Stop
alb R1 Insertional Element IS 1 at -3 promoter region
alb R2 Insertional Element IS1 at 344
alb R3 Deletion deletion of 64 signal peptide; L89Stop
alb R4 Insertional Element IS5 at 116
alb R5 Insertional Element IS2 at 665
alb R6 Insertional Element IS1 at 692
alb R7 Insertional Element IS1 at -16 promoter region
alb R8 Missense G161C R32P
alb R9 Deletion deletion of 4 signal peptide; L89Stop

* Indicates paired phage resistant mutants with the same mutation.