TABLE 1.

Minimum inhibitory concentration (MIC) values of brevibacillins against pathogenic bacteria.

Microorganism	MIC (mg/L)a
	Bre	Bre V	Bre I	Bre 2V	Poly B	Nisin
Gram-positive pathogenic bacteria
Staphylococcus aureus ATCC15975 (MRSA)	2	1–2	2	2	32	4–8
Enterococcus faecium LMG16003 (VRE)	2	2	2	2	16	4
Enterococcus faecalis LMG16216 (VRE)	2	2	2	2	16	4
Bacillus cereus ATCC14579	1	1	2	2	8	4
Gram-negative pathogenic bacteria
Acinetobacter baumannii ATCC17978	32	64	64	32	4	32
Escherichia coli ATCC25922	32	32	32	16	2	64
Pseudomonas aeruginosa LMG6395	64	64	64	64	1	128
Klebsiella pneumoniae LMG20218	32	64	64	32	2	128

^aThe MIC was determined by broth microdilution.

VRE, vancomycin-resistant Enterococcus; MRSA, methicillin-resistant S. aureus; Bre, brevibacillin; Bre V, brevibacillin V; Bre I, brevibacillin I; Bre 2V, brevibacillin 2V; Poly B, polymyxin B.