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. 2021 Mar 17;7(2):521–529. doi: 10.1016/j.aninu.2020.06.014

Table 4.

Hematological variables of lambs supplemented with curcumin.

Item Treatments1
SEM P-value
T0 T1 T2 T4 Treat Treat × day
Erythrocytes, × 106 μL 0.03 0.05
 d 0 8.49 8.29 7.26 7.81 0.62
 d 7 6.61 5.88 7.08 6.47 0.62
 d 12 6.20c 8.36b 10.3a 7.94b 0.66
 d 17 6.56b 7.57ab 9.41a 6.98b 0.62
Hematocrit, % 35.2 33.9 34.7 34.6 0.48 0.30 0.21
Hemoglobin, g/dL 11.3 10.7 11.1 11.2 0.19 0.13 0.22
Leukocytes, × 103/μL 0.05 <0.0001
 d 0 10.2 9.98 9.56 8.58 0.60
 d 7 9.34a 7.44b 7.18b 7.40b 0.60
 d 12 6.57a 5.47c 5.85ab 6.02ab 0.60
 d 17 6.78b 5.20c 6.09bc 9.92a 0.60
Neutrophils, × 103/μL 0.02 <0.0001
 d 0 3.66 3.28 3.11 3.08 0.31
 d 7 3.99a 2.40b 2.37b 2.00b 0.31
 d 12 2.87a 1.91b 2.29ab 1.95b 0.35
 d 17 2.53b 2.16b 2.56b 4.59a 0.31
Lymphocytes, × 103/μL 0.33 0.04
 d 0 5.64 6.23 6.12 5.16 0.43
 d 7 5.39 4.81 4.51 5.11 0.43
 d 12 3.52 3.28 2.70 3.60 0.49
 d 17 4.75a 2.89b 3.17b 4.90a 0.43
Monocytes, × 103/μL 0.12 0.11 0.11 0.13 0.94 0.94 0.71
Eosinophils, × 103/μL 0.09 0.09 0.10 0.09 0.02 0.97 0.84

a, b, c Within a row, means without out a common superscript differs (P ≤ 0.05) or tends to differ (P ≤ 0.10) between treatments.

1

T0, T1, T2 and T4 represents supplementation of polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) at 0, 1, 2 and 4 mg/kg concentrate, respectively.