Table 5.
Serum biochemistry of lambs supplemented with curcumin nanocapsules.
Item | Treatments1 |
SEM |
P-value |
||||
---|---|---|---|---|---|---|---|
T0 | T1 | T2 | T4 | Treat | Treat × day | ||
AST, U/L | 113b | 119ab | 134a | 134a | 6.31 | 0.09 | 0.68 |
GGT, U/L | 0.09 | 0.07 | |||||
d 0 | 101 | 98.3 | 102 | 102 | 5.75 | ||
d 7 | 96.2b | 112a | 95.6b | 115a | 5.75 | ||
d 12 | 113b | 116b | 103b | 132a | 5.75 | ||
d 17 | 121 | 114 | 112 | 113 | 5.75 | ||
Protein total, g/dL | <0.0001 | 0.0003 | |||||
d 0 | 5.25 | 5.61 | 5.26 | 5.34 | 0.31 | ||
d 7 | 6.84b | 5.90c | 6.23b | 6.99a | 0.31 | ||
d 12 | 6.46a | 5.01b | 5.54b | 5.58b | 0.31 | ||
d 17 | 5.44a | 4.34b | 5.09ab | 5.20ab | 0.31 | ||
Albumin, g/dL | 0.64 | 0.08 | |||||
d 0 | 2.78 | 3.18 | 3.23 | 2.96 | 0.21 | ||
d 7 | 4.03a | 3.34bc | 3.12c | 3.65b | 0.21 | ||
d 12 | 2.63a | 2.49ab | 2.14b | 2.53ab | 0.21 | ||
d 17 | 3.20 | 3.64 | 3.62 | 3.60 | 0.21 | ||
Globulin, g/dL | 0.01 | 0.01 | |||||
d 0 | 2.40 | 2.48 | 2.05 | 2.36 | 0.34 | ||
d 7 | 2.75a | 1.61b | 3.13a | 3.33a | 0.34 | ||
d 12 | 3.75a | 2.57b | 3.44ab | 3.03ab | 0.34 | ||
d 17 | 2.17a | 1.26b | 1.51b | 1.60ab | 0.34 | ||
Glucose, mg/dL | 0.12 | 0.07 | |||||
d 0 | 90.8 | 88.3 | 98.5 | 88.8 | 4.57 | ||
d 7 | 86.6 | 88.2 | 85.5 | 79.3 | 4.57 | ||
d 12 | 78.6a | 71.0ab | 65.4b | 64.6b | 4.57 | ||
d 17 | 78.0ab | 81.3a | 58.6c | 68.1bc | 4.58 | ||
Triglycerides, mg/dL | 0.43 | 0.04 | |||||
d 0 | 59.8 | 46.4 | 52.6 | 56.0 | 4.68 | ||
d 7 | 48.1b | 63.2a | 69.6a | 67.2a | 4.68 | ||
d 12 | 36.9 | 34.4 | 32.3 | 38.3 | 4.68 | ||
d 17 | 41.9 | 51.7 | 45.3 | 49.6 | 4.68 | ||
Urea, mg/dL | 0.84 | 0.02 | |||||
d 0 | 29.0 | 27.0 | 25.7 | 22.0 | 3.05 | ||
d 7 | 25.6b | 31.8ab | 31.0ab | 34.1a | 3.05 | ||
d 12 | 37.0 | 34.1 | 37.1 | 35.1 | 3.05 | ||
d 17 | 33.9b | 38.7a | 43.1a | 42.3a | 3.05 |
AST = aspartate aminotransferase; GGT = gamma glutamyltransferase.
a-c Within a row, means without out a common superscript differs (P ≤ 0.05) or tends to differ (P ≤ 0.10) between treatments.
T0, T1, T2 and T4 represents supplementation of polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) at 0, 1, 2 and 4 mg/kg concentrate, respectively.