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. 2021 Mar 17;7(2):521–529. doi: 10.1016/j.aninu.2020.06.014

Table 5.

Serum biochemistry of lambs supplemented with curcumin nanocapsules.

Item Treatments1
SEM P-value
T0 T1 T2 T4 Treat Treat × day
AST, U/L 113b 119ab 134a 134a 6.31 0.09 0.68
GGT, U/L 0.09 0.07
 d 0 101 98.3 102 102 5.75
 d 7 96.2b 112a 95.6b 115a 5.75
 d 12 113b 116b 103b 132a 5.75
 d 17 121 114 112 113 5.75
Protein total, g/dL <0.0001 0.0003
 d 0 5.25 5.61 5.26 5.34 0.31
 d 7 6.84b 5.90c 6.23b 6.99a 0.31
 d 12 6.46a 5.01b 5.54b 5.58b 0.31
 d 17 5.44a 4.34b 5.09ab 5.20ab 0.31
Albumin, g/dL 0.64 0.08
 d 0 2.78 3.18 3.23 2.96 0.21
 d 7 4.03a 3.34bc 3.12c 3.65b 0.21
 d 12 2.63a 2.49ab 2.14b 2.53ab 0.21
 d 17 3.20 3.64 3.62 3.60 0.21
Globulin, g/dL 0.01 0.01
 d 0 2.40 2.48 2.05 2.36 0.34
 d 7 2.75a 1.61b 3.13a 3.33a 0.34
 d 12 3.75a 2.57b 3.44ab 3.03ab 0.34
 d 17 2.17a 1.26b 1.51b 1.60ab 0.34
Glucose, mg/dL 0.12 0.07
 d 0 90.8 88.3 98.5 88.8 4.57
 d 7 86.6 88.2 85.5 79.3 4.57
 d 12 78.6a 71.0ab 65.4b 64.6b 4.57
 d 17 78.0ab 81.3a 58.6c 68.1bc 4.58
Triglycerides, mg/dL 0.43 0.04
 d 0 59.8 46.4 52.6 56.0 4.68
 d 7 48.1b 63.2a 69.6a 67.2a 4.68
 d 12 36.9 34.4 32.3 38.3 4.68
 d 17 41.9 51.7 45.3 49.6 4.68
Urea, mg/dL 0.84 0.02
 d 0 29.0 27.0 25.7 22.0 3.05
 d 7 25.6b 31.8ab 31.0ab 34.1a 3.05
 d 12 37.0 34.1 37.1 35.1 3.05
 d 17 33.9b 38.7a 43.1a 42.3a 3.05

AST = aspartate aminotransferase; GGT = gamma glutamyltransferase.

a-c Within a row, means without out a common superscript differs (P ≤ 0.05) or tends to differ (P ≤ 0.10) between treatments.

1

T0, T1, T2 and T4 represents supplementation of polymethacrylate (Eudragit L-100) nanocapsules loaded with curcumin (N-CU) at 0, 1, 2 and 4 mg/kg concentrate, respectively.