. 2021 Apr 20;11(6):1629–1647. doi: 10.1016/j.apsb.2021.04.011

Table 1.

Inhibitory activity of natural products isolated from D. cambodiana against 5-LOX.

Compd.	Activated PMNL	Human recombinant 5-LOX	Compd.	Activated PMNL
1	0.34 ± 0.03^a	0.50 ± 0.17^a	10	65.7 ± 5.7^b
2	0.28 ± 0.06^a	0.50 ± 0.23^a	11	89.2 ± 6.7^b
3	0.80 ± 0.14^a	0.30 ± 0.07^a	12	5.0 ± 1.4^a
4	0.46 ± 0.12^a	0.90 ± 0.26^a	13	60.1 ± 8.2^b
5	0.51 ± 0.12^a	1.10 ± 0.28^a	14	8.9 ± 1.6^a
6	0.85 ± 0.15^a	0.30 ± 0.09^a	15	6.5 ± 0.4^a
7	0.59 ± 0.16^a	0.60 ± 0.16^a	16	4.4 ± 0.7^a
8	67.4 ± 6.2^b	n.d.	17	7.2 ± 0.9^a
9	5.7 ± 0.9^a	n.d.	18	n.i.

IC₅₀ values (μmol/L).

Residual activities at 10 μmol/L (% control) are given as means ± SEM, n = 3. n.i., no inhibition; n.d., not determined.