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. 2021 Mar 19;118(11):188–194. doi: 10.3238/arztebl.m2021.0121

eTable 1. Strength of recommendation and level of evidence.

Grade Strength of recommendation
A High strength of recommendation
B Medium strength of recommendation
0 Low strength of recommendation
Grade Level of evidence
Ia Highest level, evidence from meta-analyses or systematic reviews of randomized controlled trials
Ib Evidence from individual randomized controlled studies
II Evidence from cohort studies
III Evidence from case-control studies
IV Evidence from case series
V Expert consensus with systematic literature search, no studies found
GCP Expert consensus without a systematic literature search: Good Clinical Practice