Table 1.

Criteria for the validity assessment of animal models.

Face validity	Reflects the degree of similarity in clinical and pathological presentation of the animal model with the human disease.
Construct validity	Reflects the degree of similarity in disease mechanisms between the animal model and the human disease.
Predictive validity	Reflects the extent to which the animal model correctly predicts the clinical success of an experimental therapy.
External validity	Reflects whether the animal model produces comparable results in different research facilities.