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Apoptosis effects of HepG2 cells induced by compound 12. HepG2 cells were treated with different concentrations (0.0, 2.0, 4.0, and 8.0 μmol/L) of 12 for 48 h. (A) and (B) Flow cytometric analysis and cell apoptosis quantification of HepG2 cells. (C) and (D) Western blot and statistical results of BCL-2, PARP-1, and cleaved-PARP-1. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001, n = 3.
