Table 6.

Cytotoxicity of compounds 1–23 from A. atrovirens.

No.	IC50 (μmol/L)
	HepG2	SMMC-7721	Huh7
1	4.4 ± 0.2	9.6 ± 0.3	7.6 ± 0.3
2	35.7 ± 1.0	86.6 ± 4.4	35.1 ± 0.4
3	5.5 ± 0.3	22.5 ± 2.7	5.4 ± 0.4
4	21.1 ± 2.9	85.4 ± 7.0	85.0 ± 3.9
5	3.3 ± 0.8	18.7 ± 1.9	5.7 ± 0.2
6	116.9 ± 4.3	8.9 ± 0.1	4.5 ± 0.2
7	6.0 ± 0.1	43.8 ± 1.4	18.6 ± 0.2
8	12.7 ± 1.9	8.9 ± 0.3	5.9 ± 0.3
9	33.4 ± 6.2	111.9 ± 8.8	70.3 ± 2.6
10	10.3 ± 3.1	24.4 ± 0.2	8.2 ± 0.3
11	58.6 ± 7.2	12.9 ± 0.3	9.1 ± 0.3
12	3.8 ± 0.4	4.6 ± 1.1	4.5 ± 0.1
13	5.3 ± 0.2	17.2 ± 1.3	4.0 ± 0.1
14	7.6 ± 0.2	6.6 ± 0.1	6.9 ± 0.1
15	6.7 ± 0.1	6.0 ± 0.3	5.6 ± 0.2
16	8.8 ± 0.2	24.4 ± 1.3	16.5 ± 0.5
17	19.5 ± 0.8	22.3 ± 0.1	8.4 ± 0.1
18	25.7 ± 2.2	11.4 ± 1.9	16.3 ± 0.1
19	7.1 ± 0.1	75.4 ± 2.3	99.3 ± 7.3
20	13.0 ± 0.3	21.6 ± 2.0	10.4 ± 0.2
21	28.8 ± 0.2	10.1 ± 0.5	16.7 ± 0.5
22	6.4 ± 0.1	47.2 ± 1.3	36.3 ± 0.4
23	33.4 ± 0.9	21.9 ± 0.4	20.6 ± 0.3
Sorafenib	7.7 ± 0.4	9.9 ± 0.8	8.3 ± 0.4

Data were expressed as means ± SD (n = 3).