Table 1. Comparison of HRCT imaging features and pathological growth patterns of GGN with different metabolic levels in FDG PET.
| Groups | Total (n=177) | Tertile 1 (n=55) | Tertile 2 (n=60) | Tertile 3 (n=62) | P value |
|---|---|---|---|---|---|
| Number, n (%) | 0.843 | ||||
| Single | 98 (55.4) | 29 (52.7) | 33 (55.0) | 36 (58.1) | |
| Multiple | 79 (44.6) | 26 (47.3) | 27 (45.0) | 26 (41.9) | |
| Type, n (%) | <0.001 | ||||
| pGGN | 53 (29.9) | 31 (56.4) | 18 (30.0) | 4 (6.5) | |
| mGGN | 124 (70.1) | 24 (43.6) | 42 (70.0) | 58 (93.5) | |
| Location, n (%) | 0.411 | ||||
| Periphery | 169 (95.5) | 52 (94.5) | 59 (98.3) | 58 (93.5) | |
| Center | 8 (4.5) | 3 (5.5) | 1 (1.7) | 4 (6.5) | |
| Shape, n (%) | <0.001 | ||||
| Round/quasi-round | 97 (54.8) | 42 (76.4) | 27 (45.0) | 28 (45.2) | |
| Irregular | 80 (45.2) | 13 (23.6) | 33 (55.0) | 34 (54.8) | |
| Edge, n (%) | <0.001 | ||||
| Smooth | 86 (48.6) | 42 (76.4) | 28 (46.7) | 16 (25.8) | |
| Lobulated | 91 (51.4) | 13 (23.6) | 32 (53.3) | 46 (74.2) | |
| Bronchial sign, n (%) | 137 (77.4) | 33 (60.0) | 48 (80.0) | 56 (90.3) | <0.001 |
| Vacuole sign, n (%) | 28 (15.8) | 5 (9.1) | 6 (10.0) | 17 (27.4) | 0.008 |
| Pleural depression sign, n (%) | 117 (66.1) | 23 (41.8) | 42 (70.0) | 52 (83.9) | <0.001 |
| Vessel convergence sign, n (%) | 168 (94.9) | 47 (85.5) | 59 (98.3) | 62 (100.0) | <0.001 |
| DGGN (mm) | 19.8±6.6 | 13.7±4.5 | 22.1±5.3 | 23.1±5.4 | <0.001 |
| Dsolid (mm) | 7.6±6.8 | 2.7±3.8 | 6.8±6.4 | 12.9±5.5 | <0.001 |
| CTR | 0.4±0.3 | 0.2±0.2 | 0.3±0.3 | 0.6±0.2 | <0.001 |
| CTGGO (HU) | −460.0±131.7 | −514.3±144.8 | −457.4±127.2 | −414.2±105.0 | <0.001 |
| ÄCTGGO-LP (HU) | 402.1±120.4 | 354.5±130.9 | 405.9±123.3 | 440.5±91.5 | <0.001 |
| Growth pattern, n (%) | <0.001 | ||||
| LPL | 50 (28.2) | 26 (47.3) | 16 (26.7) | 8 (12.9) | |
| INV | 127 (71.8) | 29 (52.7) | 44 (73.3) | 54 (87.1) |
The results are expressed as mean ± (SD) / N (%). HRCT, high-resolution computed tomography; pGGN, pure ground-glass nodule, mGGN, mixed ground-glass nodule, DGGN, diameter of the GGN, Dsolid, diameter of the solid component, CTGGO: attenuation value of the GGO component on CT. CTR, Dsolid/DGGN; ÄCTGGO-LP, CTGGO − CTLP.