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. 2021 Aug;11(8):3604–3618. doi: 10.21037/qims-20-1365

Table 8. Comparison of unnecessary FNAB rates for the diagnosis of thyroid cancer in all nodules.

Guidelines FNABs,
n (%)
Malignant nodules among FNAB nodules, n (%) Benign nodules among FNAB nodules (A), n (%) Unnecessary FNAB rate (%) False-positive rate§ (%)
ACR-TIRADS 2017 679 (29.41) 274 (40.35) 405 (59.65) 17.54 (A/2,309) 28.56 (405/1,418)
ATA 2016 879 (39.94) 265 (30.14) 614 (69.86) 27.90 (A/2,201) 45.75 (614/1,342)
K-TIRADS 2016 946 (40.97) 284 (30.02) 662 (69.98) 28.67 (A/2,309) 46.69 (662/1,418)
C-TIRADS 2020 891 (38.59) 369 (41.41) 522 (58.59) 22.61 (A/2,309) 36.81 (522/1,418)

Data in parentheses are percentages for no. of FNABs, no. of malignant nodules among FNAB nodules, and no. of benign nodules among FNAB nodules. §, data in parentheses are the raw data from which the false-positive rate was calculated. FNAB, fine-needle aspiration biopsy; ACR-TIRADS 2017, the Thyroid Imaging Reporting and Data System of 2017 American College of Radiology (10); ATA 2016, the 2016 American Thyroid Association guideline (11); K-TIRADS 2016, the Thyroid Imaging Reporting and Data System of 2016 Korean Thyroid Association/Korean Society of Thyroid Radiology (5); C-TIRADS 2020, the 2020 Chinese Thyroid Imaging Reporting and Data System (3).