. 2021 Jun 7;12(25):8892–8899. doi: 10.1039/d1sc01263k

Dissociation constants (K_d/nM) for binding of monodisperse BTA dimers to protein fibrils measured using fluorescent titrations in PBS 1× at pH 7.4 and 298 K^a.

Compound	n	α-Synuclein	Protein Aβ42	Tau
13	3	—	—	—
14	6	190 ± 140	1400 ± 1600	900 ± 700
15	9	2.7 ± 1.5	78 ± 26	1000 ± 300
16	15	35 ± 15	7 ± 5	110 ± 57
17	21	210 ± 180	320 ± 75	280 ± 48

All measurements were repeated at least three times, and the errors are quoted at the 95% confidence limit. n is the number of ethylene glycol units in the linker.

Dissociation constants (Kd/nM) for binding of monodisperse BTA dimers to protein fibrils measured using fluorescent titrations in PBS 1× at pH 7.4 and 298 Ka.

Dissociation constants (K_d/nM) for binding of monodisperse BTA dimers to protein fibrils measured using fluorescent titrations in PBS 1× at pH 7.4 and 298 K^a.