. 2021 Jun 16;50:100976. doi: 10.1016/j.dcn.2021.100976

Table 3.

Critical regions showing significant top- or bottom-ranking developmental changes for each age span.

Top-Ranking Regions¹	t values²	p-values³	Bottom-Ranking Regions¹	t values²	p-values³
Age Span 0-1
Thalamus_R	8.821	<.001	Frontal_Sup_L	−4.658	<.001
Thalamus_L	7.600	<.001	Parietal_Sup_R	−4.043	<.001
Hippocampus_R	7.374	<.001	Occipital_Sup_L	−3.757	<.001
ParaHippocampal_L	7.791	<.001	Insula_L	−4.617	<.001
Hippocampus_L	7.487	<.001	Parietal_Sup_L	−4.103	<.001
ParaHippocampal_R	5.97	<.001	Rolandic_Oper_R	−3.777	<.001
Temporal_Inf_R	6.396	<.001	Rolandic_Oper_L	−4.309	<.001
Temporal_Inf_L	5.894	<.001	Occipital_Sup_R	−5.227	<.001
Fusiform_R	5.914	<.001	Frontal_Mid_Orb_L	−4.056	<.001
Caudate_R	4.068	<.001	Calcarine_L	−5.308	<.001
Fusiform_L	5.698	<.001	Calcarine_R	−5.057	<.001
Frontal_Sup_Orb_R	4.120	<.001	Precuneus_R	−6.865	<.001
Caudate_L	4.127	<.001	Precuneus_L	−6.629	<.001
			Cuneus_R	−5.727	<.001
			Cuneus_L	−6.794	<.001
			Frontal_Mid_Orb_R	−5.898	<.001
			Supp_Motor_Area_L	−5.659	<.001
			Frontal_Sup_Medial_R	−6.903	<.001
			Supp_Motor_Area_R	−7.474	<.001
			Cingulum_Ant_L	−7.552	<.001
			Frontal_Sup_Medial_L	−9.481	<.001
			Cingulum_Ant_R	−9.131	<.001
			Paracentral_Lobule_R	−14.473	<.001
			Paracentral_Lobule_L	−19.926	<.001

Age Span 1-2
Frontal_Sup_Orb_R	7.863	<.001	Postcentral_R	−4.086	<.001
Rectus_R	7.085	<.001	Cingulum_Mid_L	−3.935	<.001
Heschl_L	5.359	<.001	Frontal_Sup_Medial_R	−4.965	<.001
Thalamus_R	5.182	<.001	Parietal_Sup_R	−5.179	<.001
Hippocampus_L	6.878	<.001	Cingulum_Post_R	−3.627	<.001
ParaHippocampal_L	7.531	<.001	Occipital_Inf_L	−3.930	<.001
Thalamus_L	4.460	<.001	Occipital_Mid_R	−5.949	<.001
Frontal_Sup_Orb_L	5.776	<.001	Occipital_Mid_L	−6.786	<.001
Hippocampus_R	6.650	<.001	Frontal_Sup_Medial_L	−5.375	<.001
Temporal_Sup_L	6.743	<.001	Occipital_Sup_R	−6.866	<.001
Frontal_Mid_Orb_R	5.377	<.001	Supp_Motor_Area_L	−7.446	<.001
Temporal_Inf_L	6.827	<.001	Lingual_R	−10.883	<.001
Frontal_Inf_Orb_R	6.725	<.001	Supp_Motor_Area_R	−10.686	<.001
Pallidum_L	3.750	<.001	Lingual_L	−9.988	<.001
Rectus_L	5.099	<.001	Occipital_Sup_L	−10.114	<.001
Frontal_Inf_Orb_L	5.567	<.001	Precuneus_L	−12.132	<.001
SupraMarginal_L	5.377	<.001	Precuneus_R	−11.890	<.001
Temporal_Pole_Sup_L	5.625	<.001	Calcarine_R	−10.706	<.001
Temporal_Inf_R	6.097	<.001	Cuneus_R	−9.259	<.001
Heschl_R	3.634	<.001	Calcarine_L	−12.579	<.001
Frontal_Mid_Orb_L	4.017	<.001	Cuneus_L	−11.836	<.001
Temporal_Sup_R	5.180	<.001	Paracentral_Lobule_R	−18.299	<.001
SupraMarginal_R	4.272	<.001	Paracentral_Lobule_L	−17.877	<.001
Caudate_L	4.033	<.001
Temporal_Pole_Sup_R	3.698	<.001
ParaHippocampal_R	4.169	<.001
Fusiform_L	3.756	<.001

Age Span 2-4
Thalamus_R	4.425	<.001	Occipital_Mid_L	−4.968	<.001
Thalamus_L	4.678	<.001	Occipital_Mid_R	−4.701	<.001
ParaHippocampal_L	4.892	<.001	Calcarine_L	−4.466	<.001
Frontal_Sup_Orb_R	5.237	<.001	Occipital_Sup_R	−6.504	<.001
Frontal_Sup_Orb_L	4.780	<.001	Occipital_Sup_L	−5.737	<.001
Rectus_L	4.208	<.001	Cuneus_R	−6.547	<.001
Temporal_Inf_L	4.207	<.001	Cuneus_L	−7.655	<.001

Age Span 4-6
ParaHippocampal_L	5.214	<.001	Lingual_L	−4.986	<.001
Temporal_Pole_Mid_L	4.192	<.001	Occipital_Mid_R	−5.443	<.001
Temporal_Inf_L	5.371	<.001	Calcarine_L	−5.876	<.001
Temporal_Inf_R	4.706	<.001	Cingulum_Ant_R	−5.699	<.001
			Calcarine_R	−4.623	<.001
			Cingulum_Ant_L	−6.093	<.001
			Occipital_Sup_L	−4.935	<.001
			Cuneus_R	−4.945	<.001
			Occipital_Sup_R	−6.914	<.001
			Cuneus_L	−4.977	<.001

The naming of AAL regions is adopted from Liu et al., 2014.

The t values indicate difference between region and whole-brain mean.

The p-values are FDR corrected.