Table 3. Probable risk factors of meibomian gland loss in young and elderly patients.
| Variables | Young patients (n=91)a | Elderly patients (n=92)b | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | ||||||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | ||||
| Gender | |||||||||||
| Male | Reference | Reference | Reference | ||||||||
| Female | 3.00 (1.36–6.63) | 0.007 | 0.27 (0.08–0.93) | 0.038 | 1.06 (0.47–2.36) | 0.893 | |||||
| Age | 0.97 (0.91–1.02) | 0.227 | – | – | 1.06 (1.01–1.10) | 0.010 | 1.06 (1.01–1.11) | 0.011 | |||
| Total Demodex | 1.01 (0.96–1.06) | 0.826 | – | – | 1.02 (0.97–1.07) | 0.471 | |||||
| D. brevis % | 6.67 (1.48–30.1) | 0.014 | 28.6 (3.37–243) | 0.002 | 4.11 (0.71–23.7) | 0.113 | 4.02 (0.68–23.8) | 0.125 | |||
| BUT | 0.89 (0.81–0.98) | 0.019 | 0.91 (0.81–1.01) | 0.106 | 1.00 (0.93–1.07) | 0.935 | |||||
| TMH | 0.02 (0.00–0.57) | 0.023 | 0.07 (0.00–4.49) | 0.208 | 0.46 (0.02–8.92) | 0.608 | |||||
| Lid margin abnormalities | 2.88 (1.85–4.49) | <0.001 | 2.86 (1.47–5.57) | 0.002 | 0.99 (0.68–1.46) | 0.965 | |||||
| Eyelash disorder | 2.39 (1.10–5.22) | 0.029 | 1.28 (0.44–3.70) | 0.653 | 1.08 (0.45–2.57) | 0.863 | |||||
Variables which P<0.15 were included in the multivariate ordinal logistic regression analysis. CI, confidence interval; OR, odds ratio; BUT, tear break-up time; TMH, tear meniscus height. D. brevis, Demodex brevis; D. brevis %, D. brevis/total Demodex.