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. 2021 May;9(9):761. doi: 10.21037/atm-19-4511

Figure 3.

Figure 3

The diagnostic value of CYR61 and the distinction between MIBCs and NMIBCs preoperatively in the urine samples. (A) Urine concentration of CYR61 in NMIBCs and MIBCs. Significance was assessed by Wilcoxon rank sum test (P<0.001). (B) ROC curves of CYR61 in discriminating between NMIBCs and MIBCs; AUC was 0.883 (95% CI: 0.804–0.962) for MIBCs vs. NMIBCs (P<0.001), with 72.7% sensitivity and 86.0% specificity. CYR61, cysteine-rich angiogenic inducer 61; NMIBC, non-muscle-invasive bladder cancer; MIBC, muscle-invasive bladder cancer; ROC, receiver-operating characteristic; AUC, area under the curve; CI, confidence interval.