Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May;9(9):761. doi: 10.21037/atm-19-4511

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Transiently silenced CYR61 decreased migration and invasion in T24 and J82 cells. CYR61-siNC: interference of negative control group; CYR61-siRNA: silence of CYR61 in T24 and J82 cells. (A) Decreased migration though transwell chamber migration assay (P<0.05), scale bars: 120 µm. (B) Wound closure in scratch wounding migration assay (100×). Photographs were taken at 24 h. (C) Downregulated expression of MMP-2 (P=0.025) and NRP-1 (P=0.031). CYR61, cysteine-rich angiogenic inducer 61; MMP-2, matrix metalloproteinase-2; NRP-1, neuropilin-1.