Table 5. Comparison of the main features of three carbapenemase detection methods.
| Parameter | NG-Test CARBA 5 | mCIM/eCIM | Xpert® CARBA R |
|---|---|---|---|
| Sample type | Bacterial colonies, blood cultures | Bacterial colonies | Bacterial colonies, rectal swabs |
| Cost | Moderate | Low | High |
| Special instruments required | No | No | Yes |
| Experiment simplicity | Simple | Moderate | Simple |
| Time-to-result | 15 min | 18–24 h | 1 h |
| Result interpretation | Simple | Moderate | Simple |
| Cover range for carbapenemase | KPC, NDM, VIM, IMP, OXA-48-like | Serine carbapenemase, MBL | KPC, NDM, VIM, IMP, OXA-48-like |
mCIM, modified carbapenem inactivation method in conjunction; eCIM, EDTA carbapenem inactivation method; KPC, Klebsiella pneumoniae carbapenemase; NDM, New Delhi metallo-β-lactamase; VIM, Verona integron-encoded metallo-beta-lactamase; IMP, imipenemase; OXA, oxacillin-hydrolyzing class D beta-lactamase.