Figure 11.

Intrinsic mechanical properties of the subchondral bone trabecular. As early as 8 weeks, alterations in the trabecular bone led to decreased hardness and elastic modulus in the diabetes-osteoarthritis (DM-OA) group. (A) Representative microindentation load-displacement curve from the subchondral bone trabecular; (B) optical microscope image of subchondral bone trabecular showing approximate microindentation positions as a function of measured; (C) results were produced by using the loading protocol for the tissue properties of the mouse bones. The data were expressed as the mean ± SD and were compared using ANOVA and the Student-Newman-Keuls post-hoc test between the groups. *, P<0.05 was considered significant.