Table 4. The diagnostic analyses of upregulated and downregulated miRNAs.

MiRNAs	AUC	95% CI	P value
Upregulated
miR-455-3p	0.66	0.55–0.77	0.001
miR-135b-5p	0.89	0.85–0.93	<0.001
let-7a-3p	0.53	0.40–0.66	0.57
miR-455-3p+miR-135b-5p	0.89	0.86–0.93	<0.001
miR-455-3p+let-7a-3p	0.66	0.55–0.77	0.002
miR-135b-5p+let-7a-3p	0.92	0.89–0.95	<0.001
miR-455-3p+miR-135b-5p+let-7a-3p	0.91	0.88–0.94	<0.001
Downregulated
miR-195-5p	0.77	0.71–0.83	<0.001
miR-204-5p	0.79	0.72–0.85	<0.001
miR-149-5p	0.70	0.61–0.80	<0.001
miR-143-3p	0.79	0.71–0.87	<0.001
miR-195-5p+miR-204-5p	0.82	0.76–0.88	<0.001
miR-195-5p+miR-149-5p	0.81	0.76–0.86	<0.001
miR-195-5p+miR-143-3p	0.84	0.78–0.90	<0.001
miR-204-5p+miR-149-5p	0.80	0.73–0.86	<0.001
miR-204-5p+miR-143-3p	0.93	0.90–0.96	<0.001
miR-149-5p+miR-143-3p	0.84	0.76–0.91	<0.001
miR-195-5p+miR-204-5p+miR-149-5p	0.83	0.78–0.89	<0.001
miR-195-5p+miR-204-5p+miR-143-3p	0.93	0.90–0.96	<0.001
miR-204-5p+miR-149-5p+miR-143-3p	0.94	0.91–0.97	<0.001
miR-195-5p+miR-149-5p+miR-143-3p	0.89	0.84–0.94	<0.001
miR-195-5p+miR-204-5p+miR-149-5p+miR-143-3p	0.94	0.91–0.97	<0.001

AUC, Area Under Curve; CI, confidence interval.