Table 2. Serum periostin level at AE-FIP onset and its correlation with clinical characteristics.
| R | P value | |
|---|---|---|
| Before AE-FIP | ||
| %FVC (L) | −0.59 | 0.004* |
| %DLco (%) | −0.48 | 0.027* |
| ILD-GAP score | 0.40 | 0.04* |
| At the onset of AE-FIP | ||
| WBC (×103/μL) | 0.15 | 0.36 |
| CRP (mg/dL) | 0.04 | 0.84 |
| HMGB-1 (ng/mL) | 0.18 | 0.32 |
| LDH (IU/L) | −0.04 | 0.82 |
| D-dimer (μg/mL) | 0.29 | 0.11 |
| P/F ratio | −0.18 | 0.28 |
| BNP (pg/mL) | 0.45 | 0.01* |
| KL-6 (U/mL) | −0.02 | 0.90 |
| SP-D (ng/mL) | −0.10 | 0.57 |
| SP-A (ng/mL) | −0.18 | 0.33 |
| UIP pattern | 0.41 | 0.01* |
| GGO score | −0.12 | 0.52 |
| Fibrosis score | 0.44 | 0.01* |
| Diffuse pattern | 0.06 | 0.74 |
| APACHE II score | 0.03 | 0.87 |
*P≤0.05. %FVC, %forced vital capacity; %DLco, diffusing capacity for carbon monoxide; ILD-GAP; P/F ratio, PaO2/FiO2 ratio; CRP, C-reactive protein; LDH, lactate dehydrogenase; HMGB-1, high mobility group box-1; BNP, brain natriuretic peptide; SP-D, surfactant protein-D; M-PN, monomeric periostin.