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. 2021 May;9(9):773. doi: 10.21037/atm-21-34

Figure 6.

Figure 6

NEAT1 promotes the translocation of NF-κB p65 by regulating TNFRSF1B and participates in TNF-α mediated inflammation. (A) Translocation of NF-κB p65 to the nucleus in NCM460, NF-κB p65 (green) and DAPI stained nuclei (blue) under 200× field. (B) Translocation of NF-κB p65 to the nucleus in HT-29 under 200× field. (C) The protein expression levels of TNFRSF1B, NF-κB p65 and p-NF-κB p65, as well as proliferation and inflammation-related factors IL1R1 and Caspase-4 in different groups. NEAT1, nuclear enriched abundant transcript 1; IL1R1, interleukin 1 receptor type I; TNFRSF1B, tumor necrosis factor superfamily member 1B; TNF-α, tumor necrosis factor-alpha; NF-κB, nuclear factor-kappa B.