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. 2021 Jun 23;2021:9981480. doi: 10.1155/2021/9981480

Figure 2.

Figure 2

Effect of melatonin supplementation on improving CORT-induced GR synthesis and enhanced transport and inflammation response in mice. Colonic GR (a), HSP90 (b), HSP70 (c), P23 (d), iNOS (e), COX-2 (f), TNF-α (g), IL-10 (h), p-STAT3 (i), AP-1 (j), p-P65 (k), and p-IκB (l) levels in the CON, CORT, and CORT+MT groups were measured by qRT-PCR, ELISA, and western blotting. Values are presented as the mean ± SE. Differences were assessed using ANOVA and are denoted as follows: different lowercase letters: p < 0.05; different uppercase letters: p < 0.01; and the same letter: p > 0.05.