图 4.

SP13786通过CAFs-exo对A549细胞形态、迁移及侵袭的影响。A：PTFs-exo、CAFs-exo和CAFs+SP13786-exo对A549细胞形态的影响（×100）；B：Transwell检测24 h后PTFs-exo、CAFs-exo和CAFs+SP13786-exo对A549细胞侵袭能力的影响（×200）；C、D：Transwell迁移实验（C, ×200）和划痕实验（D, ×40）检测24 h后PTFs-exo、CAFs-exo和CAFs+SP13786-exo对A549细胞迁移能力的影响。*P < 0.05；***P < 0.001。

Effects of SP13786 on the morphology, invasion and migration of A549 cells through CAFs-exo. A: The effect of PTFs-exo, CAFs-exo and CAFs+SP13786-exo on the morphology of A549 cells (×100); B: Transwell assays were performed to evaluate cell invasive ability after 24h (×200); C, D: Transwell assays (C, ×200) and wound healing assays (D, ×40) were performed to evaluate cell migration ability after 24 h. *P < 0.05; ***P < 0.001.