Figure 3.

Comparison between prediabetes and NGT proteomes

The volcano plots of differentially expressed muscle proteins between IFG and NGT (left panel) or IGT and NGT (right panel). p-value was set to match q-value < 0.05. The light blue dots indicate significantly down-regulated proteins with FC < 2, and the blue dots with FC > 2. The red dots indicate significantly up-regulated proteins. Down-regulated proteins in the prediabetes samples were categorized according to their biological processes and KEGG pathways using DAVID bioinformatics tool. The most significant events are listed with Benjamini corrected p-value.