Figure 4.

Comparison between type 2 diabetes and NGT proteomes

The volcano plots of differentially expressed muscle proteins between T2D and NGT. p-value was set to match q-value < 0.05. The light blue dots indicate significantly down-regulated proteins with FC < 2 and the blue dots with FC > 2. The red dots indicate significantly upregulated proteins. Downregulated and upregulated proteins in the T2D samples were categorized as per their biological processes and KEGG pathways using DAVID bioinformatics tool. The most significant events are listed with Benjamini corrected p-value.