TABLE 1.
Baseline characteristics according to the SCFA PGS1
| Tertiles of the PGS | ||||
|---|---|---|---|---|
| Tertile 1 | Tertile 2 | Tertile 3 | P 2 | |
| n | 124 | 144 | 102 | |
| Age, y | 53 ± 8 | 52 ± 9 | 52 ± 10 | 0.84 |
| Female, n (%) | 79 (64) | 69 (47.9) | 55 (53.9) | 0.03 |
| Race, n (%) | <0.01 | |||
| Non-white | 31 (25) | 15 (10) | 3 (3) | |
| White | 93 (75) | 129 (90) | 99 (97) | |
| BMI, kg/m2 | 33 ± 4 | 33 ± 4 | 33 ± 4 | 0.39 |
| Height, cm | 169 ± 9 | 171 ± 9 | 169 ± 9 | 0.80 |
| Weight, kg | 93 ± 16 | 95 ± 15 | 94 ± 15 | 0.47 |
| Spine BMD, g/cm2 | 1.069 ± 0.135 | 1.066 ± 0.148 | 1.025 ± 0.148 | 0.523 |
| Femoral hip BMD, g/cm2 | 1.024 ± 0.131 | 1.020 ± 0.128 | 1.006 ± 0.144 | 0.963 |
| Whole-body BMD, g/cm2 | 1.134 ± 0.097 | 1.137 ± 0.111 | 1.124 ± 0.114 | 0.463 |
| Dietary intake per day | ||||
| Energy, kcal | 1910 ± 532 | 2037 ± 526 | 1991 ± 598 | 0.09 |
| Carbohydrate, % | 46 ± 8 | 43 ± 7 | 45 ± 7 | 0.19 |
| Fat, % | 36 ± 6 | 38 ± 6 | 37 ± 5 | 0.85 |
| Protein, % | 18 ± 3 | 18 ± 3 | 18 ± 3 | 0.25 |
| Dietary calcium, mg/d | 880 ± 528 | 906 ± 442 | 940 ± 525 | 0.16 |
| Dietary fiber, g/d | 12.4 ± 5.5 | 12.5 ± 5.6 | 13.5 ± 6.7 | 0.10 |
| Physical activity score4 | 1.6 ± 0.1 | 1.6 ± 0.1 | 1.6 ± 0.1 | 0.82 |
1
Values are means ± SDs unless otherwise indicated. BMD, bone mineral density; PGS, polygenic score.
2
P values were calculated using the chi-square test for categorical variables and general linear models (PROC GLM) for continuous variable.
3
Data were adjusted for age, race, sex, BMI, baseline dietary fiber intake, baseline calcium intake, and baseline physical activity; PGS was treated as a continuous variable.
4
Physical activity score was estimated using the Baecke questionnaire.