Table 4.
The assessed OPN mRNA expression levels in the tumors and paired margins of patients with primary bone cancers. Mean (95% CI).
| Malignancy | Type | Marginal tissue | Cancerous tissue |
|---|---|---|---|
| Malignant | Osteosarcoma | 0.11 (0.04–0.17) | 4.40 (3.71–5.09)a |
| Chondrosarcoma | 0.22 (0.08–0.36) | 2.99 (2.56–3.42)b | |
| Ewing sarcoma | 0.28 (0.09–0.46) | 3.41 (2.92–3.91)ab | |
| Benign | Exostosis | 0.08 (0.01–0.15) | 0.93 (0.80–1.06)c |
| Giant Cell Tumor | 0.07 (0.03–0.11) | 1.34 (1.11 – 1.57)c | |
| Osteochondroma | 0.06 (0.02–0.11) | 1.09 (0.92–1.26)c |
Means within a column with different superscript letters (a-c) denote significant differences (p < 0.05).
Margins Vs. tumors are significantly different (P < 0.0001) within each row.