Fig. 5.

mRNA expression levels of TSP genes in skeletal muscles of mdx mice. Bar graphs showing the quantification of transcripts levels of CBS, CSE, 3-MST, CDO, CSAD, γ-GCS and GS evaluated by qPCR in QFA and gastrocnemius of control wt (n = 6) and mdx mice (n = 6). Control and mdx mice have been compared at both 7 (A–B) and 17 (C–D) weeks. Data are expressed as 2^∧-ΔΔct relative to ribosomal protein S16, as described in materials and methods. Differences are considered statistically significant when p was ≤0.05. Single asterisk (*), double-asterisk (**) and triple asterisk (***) denote a p-value of ≤0.05, 0.01 and 0.001 vs wt mice.