Table 1.

Representative list of therapeutic proteins produced in yeast

Host	Therapeutic protein	Yield	Reference
P. pastoris	Insulin	3 g/L Insulin precursor	[122]
S. cerevisiae	IFNα2b	15 mg/L	[142]
Y. lipolytica	IFNα2b	425 mg/L	[143]
P. pastoris	Hepatitis B antigen	7 g/L	[144]
S. cerevisiae	Glucagon like peptide 2	–	[145]
K. lactis	Human interferon β	–	[40]
P. pastoris	Human granulocyte–macrophage colony-stimulating factor	285 mg/L	[146]
P. pastoris	Human serum albumin	92.29 mg/L	[147]
H. polymorpha	HBV surface antigen	250 mg/L	[148]
H. polymorpha	Granulocyte colony stimulating factor (GCSF)	–	[26]
H. polymorpha	Rotavirus VP6 protein (RV VP6)	3350.71 mg/L	[149]
H. polymorpha	HPV type 16 L1-L2 chimeric protein (SAF)	132.10 mg/L	[25]