Table 3.

Radioactivity of ¹⁴C-lidocaine in the serum

	Lidocaine Mean ± SD	Lidocaine with epinephrine Mean ± SD	p value
Sample size	12	12
Time (min)
0.5	19.1 ± 9.2	15.6 ± 6.7	0.291
2	21.8 ± 10.4	24.8 ± 5.6	0.383
5	34.1 ± 9.5	30.7 ± 6.6	0.322
10	55.9 ± 4.3	40.9 ± 4.8	< 0.001
20	76.9 ± 8.2	48.4 ± 8.6	< 0.001
30	63.4 ± 7.8	59.8 ± 4.7	0.189
40	49.3 ± 5.7	70.2 ± 4.4	< 0.001
50	34.8 ± 7.3	88.2 ± 2.9	< 0.001
60	20.6 ± 9.5	81.0 ± 4.8	< 0.001

Data presented as the mean of ¹⁴C radioactivity in dpm/1 mL serum

p value compares lidocaine versus lidocaine with epinephrine

Unpaired t-test used to compare means

SD standard deviation