Table 5.
100 Highest-Cited Publications in TCAIM Journals
| Position | Title | Authors | Year | Source Title | Citation Count |
|---|---|---|---|---|---|
| 1 | Natural products as sources of new drugs over the last 25 years | Newman D.J., Cragg G.M. | 2007 | Journal of Natural Products | 3258 |
| 2 | Flavonoids as antioxidants | Pietta P.-G. | 2000 | Journal of Natural Products | 3162 |
| 3 | Natural products as sources of new drugs over the 30 years from 1981 to 2010 | Newman D.J., Cragg G.M. | 2012 | Journal of Natural Products | 3122 |
| 4 | Brine shrimp: A convenient general bioassay for active plant constituents | Meyer B.N., Ferrigni N.R., Putnam J.E., Jacobsen L.B., Nichols D.E., McLaughlin J.L. | 1982 | Planta Medica | 2939 |
| 5 | Natural products as sources of new drugs from 1981 to 2014 | Newman D.J., Cragg G.M. | 2016 | Journal of Natural Products | 2750 |
| 6 | Natural products as sources of new drugs over the period 1981–2002 | Newman D.J., Cragg G.M., Snader K.M. | 2003 | Journal of Natural Products | 2285 |
| 7 | Free radicals, antioxidants and functional foods: Impact on human health | Lobo V., Patil A., Phatak A., Chandra N. | 2010 | Pharmacognosy Reviews | 1939 |
| 8 | Pharmacology of Curcuma longa | Ammon H.P.T., Wahl M.A. | 1991 | Planta Medica | 1415 |
| 9 | A sensitive and quick microplate method to determine the minimal inhibitory concentration of plant extracts for bacteria | Eloff J.N. | 1998 | Planta Medica | 1320 |
| 10 | Screening of plant extracts for antioxidant activity: A comparative study on three testing methods | Koleva I.I., Van Beek T.A., Linssen J.P.H., De Groot A., Evstatieva L.N. | 2002 | Phytochemical Analysis | 1186 |
| 11 | Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers | Shoba G., Joy D., Joseph T., Majeed M., Rajendran R., Srinivas P.S.S.R. | 1998 | Planta Medica | 1178 |
| 12 | Natural products in drug discovery and development | Cragg G.M., Newman D.J., Snader K.M. | 1997 | Journal of Natural Products | 1126 |
| 13 | Natural polyphenols (vegetable tannins) as drugs: Possible modes of action | Haslam E. | 1996 | Journal of Natural Products | 960 |
| 14 | Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement (Chinese edition) | Moher D., Liberati A., Tetzlaff J., Altman D.G., Altman D., Antes G., Atkins D., Barbour V., Barrowman N., Berlin J.A., Clark J., Clarke M., Cook D., D’Amico R., Deeks J.J., Devereaux P.J., Dickersin K., Egger M., Ernst E., Gøtzsche P.C., Grimshaw J., Guyatt G., Higgins J., Ioannidis J.P.A., Kleijnen J., Lang T., Magrini N., McNamee D., Moja L., Mulrow C., Napoli M., Oxman A., Pham B., Rennie D., Sampson M., Schulz K.F., Shekelle P.G., Tovey D., Tugwell P. | 2009 | Journal of Chinese Integrative Medicine | 933 |
| 15 | The role of natural product chemistry in drug discovery | Butler M.S. | 2004 | Journal of Natural Products | 918 |
| 16 | Natural products from endophytic microorganisms | Strobel G., Daisy B., Castillo U., Harper J. | 2004 | Journal of Natural Products | 916 |
| 17 | Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: A review of preclinical and clinical research | Jurenka J.S. | 2009 | Alternative Medicine Review | 837 |
| 18 | Dose escalation of a curcuminoid formulation | Lao C.D., Ruffin IV M.T., Normolle D., Heath D.D., Murray S.I., Bailey J.M., Boggs M.E., Crowell J., Rock C.L., Brenner D.E. | 2006 | BMC Complementary and Alternative Medicine | 833 |
| 19 | Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers | Cos P., Ying L., Calomme M., Hu J.P., Cimanga K., Van Poel B., Pieters L., Vlietinck A.J., Vanden Berghe D. | 1998 | Journal of Natural Products | 823 |
| 20 | Mindfulness-based stress reduction for stress management in healthy people: A review and meta-analysis | Chiesa A., Serretti A. | 2009 | Journal of Alternative and Complementary Medicine | 789 |
| 21 | Th1/Th2 balance: The hypothesis, its limitations, and implications for health and disease | Kidd P. | 2003 | Alternative Medicine Review | 781 |
| 22 | Annonaceous acetogenins: Recent progress | Alali F.Q., Liu X.-X., McLaughlin J.L. | 1999 | Journal of Natural Products | 745 |
| 23 | Antidiabetic plants and their active constituents | Marles R.J., Farnsworth N.R. | 1995 | Phytomedicine | 744 |
| 24 | Trends in use of complementary and alternative medicine by us adults: 1997–2002 | Tindle H.A., Davis R.B., Phillips R.S., Eisenberg D.M. | 2005 | Alternative Therapies in Health and Medicine | 724 |
| 25 | Antioxidant principles from Bauhinia tarapotensis | Braca A., De Tommasi N., Di Bari L., Pizza C., Politi M., Morelli I. | 2001 | Journal of Natural Products | 712 |
| 26 | Synergy research: Approaching a new generation of phytopharmaceuticals | Wagner H., Ulrich-Merzenich G. | 2009 | Phytomedicine | 695 |
| 27 | Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa) | Chainani-Wu N. | 2003 | Journal of Alternative and Complementary Medicine | 683 |
| 28 | Natural products from plant-associated microorganisms: Distribution, structural diversity, bioactivity, and implications of their occurrence | Gunatilaka A.A.L. | 2006 | Journal of Natural Products | 664 |
| 29 | The pharmacological potential of mushrooms | Lindequist U., Niedermeyer T.H.J., Jülich W.-D. | 2005 | Evidence-based Complementary and Alternative Medicine | 648 |
| 30 | Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation | Houghton P.J., Zarka R., De Las Heras B., Hoult J.R.S. | 1995 | Planta Medica | 641 |
| 31 | Marine natural products and related compounds in clinical and advanced preclinical trials | Newman D.J., Cragg G.M. | 2004 | Journal of Natural Products | 626 |
| 32 | Synergy and other interactions in phytomedicines | Williamson E.M. | 2001 | Phytomedicine | 621 |
| 33 | Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals | Surh Y.-J., Kundu J.K., Na H.-K. | 2008 | Planta Medica | 593 |
| 34 | Use and expenditure on complementary medicine in England: A population based survey | Thomas K.J., Nicholl J.P., Coleman P. | 2001 | Complementary Therapies in Medicine | 577 |
| 35 | In vitro antibacterial activity of some plant essential oils | Prabuseenivasan S., Jayakumar M., Ignacimuthu S. | 2006 | BMC Complementary and Alternative Medicine | 572 |
| 36 | Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries | Wang H., Nair M.G., Strasburg G.M., Chang Y.-C., Booren A.M., Gray J.I., DeWitt D.L. | 1999 | Journal of Natural Products | 572 |
| 37 | Alkaloids from amphibian skin: A tabulation of over eight-hundred compounds | Daly J.W., Spande T.F., Garraffo H.M. | 2005 | Journal of Natural Products | 558 |
| 38 | Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): A review | Mishra L.-C., Singh B.B., Dagenais S. | 2000 | Alternative Medicine Review | 538 |
| 39 | Acetylcholinesterase inhibitors from plants | Mukherjee P.K., Kumar V., Mal M., Houghton P.J. | 2007 | Phytomedicine | 522 |
| 40 | Extraction, isolation and characterization of bioactive compounds from plants’ extracts | Sasidharan S., Chen Y., Saravanan D., Sundram K.M., Yoga Latha L. | 2011 | African Journal of Traditional, Complementary and Alternative Medicines | 514 |
| 41 | Annonaceous acetogenins: A review | Rupprecht J.K., Hui Y.-H., McLaughlin J.L. | 1990 | Journal of Natural Products | 498 |
| 42 | Synergism between natural products and antibiotics against infectious diseases | Hemaiswarya S., Kruthiventi A.K., Doble M. | 2008 | Phytomedicine | 489 |
| 43 | Lead toxicity, a review of the literature. Part I: Exposure, evaluation, and treatment | Patrick L. | 2006 | Alternative Medicine Review | 481 |
| 44 | Complementary and alternative medicine use in Australia: A national population-based survey | Xue C.C.L., Zhang A.L., Lin V., Da Costa C., Story D.F. | 2007 | Journal of Alternative and Complementary Medicine | 460 |
| 45 | Traditional Chinese medicine network pharmacology: Theory, methodology and application | Li S., Zhang B. | 2013 | Chinese Journal of Natural Medicines | 455 |
| 46 | Beneficial effects of green tea: A literature review | Chacko S.M., Thambi P.T., Kuttan R., Nishigaki I. | 2010 | Chinese Medicine | 454 |
| 47 | Therapeutic applications of pomegranate (Punica granatum L.): A review | Jurenka J. | 2008 | Alternative Medicine Review | 451 |
| 48 | Recent extraction techniques for natural products: Microwave-assisted extraction and pressurised solvent extraction | Kaufmann B., Christen P. | 2002 | Phytochemical Analysis | 447 |
| 49 | Astaxanthin, a carotenoid with potential in human health and nutrition | Hussein G., Sankawa U., Goto H., Matsumoto K., Watanabe H. | 2006 | Journal of Natural Products | 429 |
| 50 | Antimicrobial activity of essential oils: A 1976–1986 literature review. Aspects of the test methods | Janssen A.M., Scheffer J.J.C., Baerheim Svendsen A. | 1987 | Planta Medica | 429 |
| 51 | Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L | Saeed N., Khan M.R., Shabbir M. | 2012 | BMC Complementary and Alternative Medicine | 426 |
| 52 | Clinical applications of N-acetylcysteine | Kelly G.S. | 1998 | Alternative Medicine Review | 422 |
| 53 | Nutritional quality of organic versus conventional fruits, vegetables, and grains | Worthington V. | 2001 | Journal of Alternative and Complementary Medicine | 421 |
| 54 | Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness | Conklin K.A. | 2004 | Integrative Cancer Therapies | 419 |
| 55 | Iridoids. A review | El-Naggar L.J., Beal J.L. | 1980 | Journal of Natural Products | 418 |
| 56 | Anti-aids agents, 11. Betulinic acid and platanic acid as anti-HIV principles from Syzigium claviflorum, and the anti-HIV activity of structurally related triterpenoids | Fujioka T., Kashiwada Y., Kilkuskie R.E., Cosentino L.M., Bailas L.M., Jiang J.B., Janzen W.P., Chen I.-S., Lee K.-H. | 1994 | Journal of Natural Products | 415 |
| 57 | Bleomycin: New perspectives on the mechanism of action | Hecht S.M. | 2000 | Journal of Natural Products | 406 |
| 58 | Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection | Vlietinck A.J., De Bruyne T., Apers S., Pieters L.A. | 1998 | Planta Medica | 404 |
| 59 | Antioxidants and cancer III: Quercetin | Lamson D.W., Brignall M.S. | 2000 | Alternative Medicine Review | 403 |
| 60 | A microwell cytotoxicity assay using Artemia salina (brine shrimp) | Solis P.N., Wright C.W., Anderson M.M., Gupta M.P., Phillipson J.D. | 1993 | Planta Medica | 403 |
| 61 | How many cancer patients use complementary and alternative medicine: A systematic review and metaanalysis | Horneber M., Bueschel G., Dennert G., Less D., Ritter E., Zwahlen M. | 2012 | Integrative Cancer Therapies | 395 |
| 62 | The BBC survey of complementary medicine use in the UK | Ernst E., White A. | 2000 | Complementary Therapies in Medicine | 395 |
| 63 | The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis part I | Zhu J.-S., Halpern G.M., Jones K. | 1998 | Journal of Alternative and Complementary Medicine | 389 |
| 64 | Therapeutic applications of whey protein | Marshall K. | 2004 | Alternative Medicine Review | 383 |
| 65 | Chemical toxins: A hypothesis to explain the global obesity epidemic | Baillie-Hamilton P.F. | 2002 | Journal of Alternative and Complementary Medicine | 377 |
| 66 | Quantitative 1H NMR: Development and potential of a method for natural products analysis | Pauli G.F., Jaki B.U., Lankin D.C. | 2005 | Journal of Natural Products | 376 |
| 67 | Antimicrobial activity of some ethnomedicinal plants used by Paliyar tribe from Tamil Nadu, India | Duraipandiyan V., Ayyanar M., Ignacimuthu S. | 2006 | BMC Complementary and Alternative Medicine | 375 |
| 68 | Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity | Potterat O. | 2010 | Planta Medica | 374 |
| 69 | Constituents of Cannabis sativa L. XVII. a review of the natural constituents | Turner C.E., Elsohly M.A., Boeren E.G. | 1980 | Journal of Natural Products | 373 |
| 70 | Recent natural products based drug development: A pharmaceutical industry perspective | Shu Y.-Z. | 1998 | Journal of Natural Products | 371 |
| 71 | Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries | Seeram N.P., Momin R.A., Nair M.G., Bourquin L.D. | 2001 | Phytomedicine | 370 |
| 72 | Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles | Chrubasik S., Pittler M.H., Roufogalis B.D. | 2005 | Phytomedicine | 368 |
| 73 | Ayurveda and traditional Chinese medicine: A comparative overview | Patwardhan B., Warude D., Pushpangadan P., Bhatt N. | 2005 | Evidence-based Complementary and Alternative Medicine | 366 |
| 74 | A-type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli | Foo L.Y., Lu Y., Howell A.B., Vorsa N. | 2000 | Journal of Natural Products | 366 |
| 75 | Historical review of medicinal plants’ usage | Petrovska B.B. | 2012 | Pharmacognosy Reviews | 363 |
| 76 | Plant sources of hepatotoxic pyrrolizidine alkaloids | Smith L.W., Culvenor C.C.J. | 1981 | Journal of Natural Products | 361 |
| 77 | Steaming of ginseng at high temperature enhances biological activity | Wang Yu Kim, Jong Moon Kim, Sang Beom Han, Seung Ki Lee, Nak Doo Kim, Park M.K., Chong Kook Kim, Park J.H. | 2000 | Journal of Natural Products | 360 |
| 78 | Recent trends and important developments in propolis research | Bankova V. | 2005 | Evidence-based Complementary and Alternative Medicine | 357 |
| 79 | Therapeutic applications of fenugreek | Basch E., Ulbricht C., Kuo G., Szapary P., Smith M. | 2003 | Alternative Medicine Review | 357 |
| 80 | Antioxidant and free radical scavenging activity of Spondias pinnata | Hazra B., Biswas S., Mandal N. | 2008 | BMC Complementary and Alternative Medicine | 354 |
| 81 | Antioxidant and radical scavenging effects of aged garlic extract and its constituents | Imai J., Ide N., Nagae S., Moriguchi T., Matsuura H., Itakura Y. | 1994 | Planta Medica | 350 |
| 82 | Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy | Laszczyk M.N. | 2009 | Planta Medica | 346 |
| 83 | Antioxidant and antimicrobial activity of Foeniculum vulgare and crithmum maritimum essential oils | Ruberto G., Baratta M.T., Deans S.G., Dorman H.J.D. | 2000 | Planta Medica | 346 |
| 84 | Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu, India | Muthu C., Ayyanar M., Raja N., Ignacimuthu S. | 2006 | Journal of Ethnobiology and Ethnomedicine | 344 |
| 85 | Lead toxicity part II: The role of free radical damage and the use of antioxidants in the pathology and treatment of lead toxicity | Patrick L. | 2006 | Alternative Medicine Review | 343 |
| 86 | A rapid and effective method for RNA extraction from different tissues of grapevine and other woody plants | Gambino G., Perrone I., Gribaudo I. | 2008 | Phytochemical Analysis | 341 |
| 87 | Benefits and requirements of vitamin D for optimal health: A review | Grant W.B., Holick M.F. | 2005 | Alternative Medicine Review | 341 |
| 88 | Antimicrobial and antioxidant activities of three Mentha species essential oils | Mimica-Dukić N., Božin B., Soković M., Mihajlović B., Matavulj M. | 2003 | Planta Medica | 338 |
| 89 | The taxane diterpenoids | Baloglu E., Kingston D.G.I. | 1999 | Journal of Natural Products | 337 |
| 90 | Flavonoids: A versatile source of anticancer drugs | Chahar M.K., Sharma N., Dobhal M.P., Joshi Y.C. | 2011 | Pharmacognosy Reviews | 332 |
| 91 | Resilience: A historical review of the construct | Tusaie K., Dyer J. | 2004 | Holistic Nursing Practice | 332 |
| 92 | α-glucosidase inhibitors from plants: A natural approach to treat diabetes | Kumar S., Narwal S., Kumar V., Prakash O. | 2011 | Pharmacognosy Reviews | 331 |
| 93 | Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test | Butterweck V., Jürgenliemk G., Nahrstedt A., Winterhoff H. | 2000 | Planta Medica | 328 |
| 94 | Stigmasterols from Typha latifolia | Greca M.D., Monaco P., Previtera L. | 1990 | Journal of Natural Products | 327 |
| 95 | Flavonoids and phenolic acids: Role and biochemical activity in plants and human | Ghasemzadeh A., Ghasemzadeh N. | 2011 | Journal of Medicinal Plant Research | 326 |
| 96 | Alternative antimicrobial approach: Nano-antimicrobial materials | Beyth N., Houri-Haddad Y., Domb A., Khan W., Hazan R. | 2015 | Evidence-based Complementary and Alternative Medicine | 324 |
| 97 | Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils | Peana A.T., D’Aquila P.S., Panin F., Serra G., Pippia P., Moretti M.D.L. | 2002 | Phytomedicine | 324 |
| 98 | Immunostimulant agents from Andrographis paniculata | Puri A., Saxena R., Saxena R.P., Saxena K.C., Srivastava V., Tandon J.S. | 1993 | Journal of Natural Products | 324 |
| 99 | The health benefits of yoga and exercise: A review of comparison studies | Ross A., Thomas S. | 2010 | Journal of Alternative and Complementary Medicine | 320 |
| 100 | Anti-inflammatory compounds of plant origin. Part II. Modulation of pro-inflammatory cytokines, chemokines and adhesion molecules | Calixto J.B., Campos M.M., Otuki M.F., Santos A.R.S. | 2004 | Planta Medica | 319 |