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. 2020 Dec 21;94(5):774–785. doi: 10.1111/cen.14387

TABLE 3.

Effects on hyperphagia and social behaviour in boys and girls separately

BOYS (N = 12) GIRLS (N = 13)
Oxytocin phase Placebo phase Oxytocin phase Placebo phase
Items investigated Median IQR Median IQR P * Median IQR Median IQR P *
Oxytocin study questionnaire
Total score 4.5 (−0.8 to 15.3) ‐4.0 (−11.3 to 0.8) 0.025 0.0 (−12.5 to 5.5) 0.0 (−6.5 to 10.0) 0.75
Better Same Worse Better Same Worse Better Same Worse Better Same Worse
Total score 7 2 3 3 1 8 0.29 6 1 6 5 2 6 1.0
Happiness 5 7 0 0 12 0 0.06 5 8 0 5 7 1 1.0
Anxious 4 8 0 1 10 1 0.25 2 9 2 0 12 1 0.5
Food seeking behaviour 4 7 1 0 8 4 0.13 1 11 1 0 13 0 1.0
Dykens change in hyperphagia
Total score 0.0 (−0.8 to 4.3) ‐3.5 (−6.0 to 0.0) 0.046 0.0 (−1.0 to 2.0) 0.0 (−2.0 to 0.0) 0.57
Better Same Worse Better Same Worse Better Same Worse Better Same Worse
Total score 5 4 3 1 4 7 0.22 3 5 5 2 7 4 1.0
Improvement social behaviour 7 2 0.18 7 4 0.55
Improvement eating behaviour 5 1 0.22 2 0 0.5

Data expressed in median (IQR) unless otherwise specified.

a

a higher score indicates more problems in behaviour.

b

a positive score indicates improvement.

*

p‐value between oxytocin and placebo phase. p‐value for variables expressed in betters, same worse, is the p‐value for better versus no difference.

Significant differences are indicated in bold.