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Worse BBB indices were associated with greater axonal injury as reflected in CSF NFL levels. Black, PWH; gray, individuals without HIV. Abbreviations: BBB, blood–brain barrier; CSAR, cerebrospinal fluid-to-serum albumin ratio; CSF, cerebrospinal fluid; HIV, human immunodeficiency virus; NFL, neurofilament light; PWH, persons living with HIV; uPAR, urokinase plasminogen activator receptor.
