FIGURE 2.

Factors that reportedly cause chronological lifespan extension in Schizosaccharomyces pombe. All the genetic and physical interactions reported so far are shown. Information on each factor's localization was based on the reports by Ding et al. (2000) and Matsuyama et al. (2006), in addition to those mentioned in the text. Dotted lines indicate factors with unknown localization. Studies in which two or more intracellular localization (e.g., nucleus and cytosol) were reported are indicated by double‐headed arrows