Table 1.
Kidneys undergoing proteomics after normothermic machine perfusion
| Kidneys with urine recirculation (URC) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall (n = 16) | Age in years | Sex | GFRa (ml/min/1.73 m2) | Hypertension | DBD (n = 8) | DCD (n = 8) | Reason for discard | CIT in hours | CIT >24 hours | NMP time in hours | Median arterial flow in ml/min | Lactate @6 hours NMP in mmol/l | Urine in ml/hour |
| Kidney 1 | 70 | male | 59 | no | X | patchy perfusion | 15.0 | 16.2 | 330 | 14.1 | 86.3 | ||
| Kidney 2 | 61 | male | 92 | no | X | esophageal cancer | 19.1 | 24.3 | 330 | 15.1 | 41.0 | ||
| Kidney 3 | 70 | male | 125 | no | X | patchy perfusion | 32.0 | X | 12.3 | 410 | 19.9 | 3.3 | |
| Kidney 4 | 58 | male | 118 | no | X | huge cyst lower pole | 10.4 | 18.6 | 330 | 2.6 | 20.0 | ||
| Kidney 5 | 73 | male | 45 | yes | X | patchy perfusion | 20.7 | 24.1 | 250 | 19.3 | 5.8 | ||
| Kidney 6 | 51 | female | 70 | no | X | renal neoplasia | 11.4 | 24.2 | 320 | 12.9 | 44.9 | ||
| Kidney 7 | 48 | male | 232 | no | X | patchy perfusion, long CIT | 51.2 | X | 15.0 | 250 | 20.0 | 111.8 | |
| Kidney 8 | 44 | female | 100 | no | X | patchy perfusion, long CIT | 36.1 | X | 24.1 | 305 | 11.2 | 16.7 | |
| Kidney 9 | 44 | female | 92 | no | X | patchy perfusion, cortical necrosis | 104.1 | X | 24.0 | 325 | 17.2 | 11.0 | |
| Kidney 10 | 49 | male | 178 | no | X | patchy perfusion | 25.3 | X | 24.3 | 510 | 10.6 | 25.4 | |
| Kidney 11 | 67 | female | 63 | no | X | patchy perfusion | 18.5 | 24.0 | 260 | 13.4 | 17.2 | ||
| Kidney 12 | 38 | male | 58 | yes | X | suspicion of pancreatic cancer | 29.2 | X | 24.4 | 365 | 15.1 | 26.3 | |
| Kidney 13 | 68 | male | 101 | no | X | patchy perfusion | 108.1 | X | 24.0 | 514 | 6.6 | 6.5 | |
| Kidney 14 | 70 | female | 119 | yes | X | stenosis of renal artery | 17.5 | 24.1 | 413 | 8.2 | 53.5 | ||
| Kidney 15 | 47 | female | 29 | no | X | vascular damage, patchy perfusion | 12.7 | 24.1 | 230 | 20.0 | 471.9 | ||
| Kidney 16 | 76 | female | 152 | yes | X | long CIT | 15.4 | 24.0 | 787 | 5.6 | 51.0 | ||
| Kidneys without urine recirculation (UR) | |||||||||||||
| Overall (n = 3) | Age in years | Sex |
GFR a (ml/min/1.73 m2 ) |
Hypertension | DBD (n = 2) | DCD (n = 1) | Reason for discard | CIT in hours | CIT >24 hours | NMP time in hours | Median arterial flow in ml/min | Lactate @6 hours NMP in mmol/l | Urine in ml/hour |
| Kidney 17 | 74 | female | 90 | yes | X | lesion on partner kidney | 22.0 | 6.2 | 486 | 4.5 | 74.2 | ||
| Kidney 18 | 78 | female | 61 | yes | X | vascular damage | 18.4 | 9.4 | 100 | 19.7 | 102.2 | ||
| Kidney 19 | 71 | female | 77 | no | X | organ size | 21.1 | 8.2 | 371 | 17.8 | 84.4 | ||
Abbreviations: DBD, donation after brain death; DCD, donation after circulatory death; CIT, cold ischemia time; NMP, normothermic machine perfusion.
a
MDRD (modification of diet in renal disease) GFR (glomerular filtration rate) calculator.