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. 2020 Sep 18;288(9):2784–2835. doi: 10.1111/febs.15531

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© 2020 The CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Fig. 5 — (A) Examples of SLC proteins transporting inorganic ions (SLC12). SLC12A1 represents the subfamily of Na⁺‐dependent cation‐Cl⁻ cotransporters (NCC), while SLC12A4 represents the subfamily of Na⁺‐independent cation‐ Cl⁻ cotransporters (KCC). (B) Examples of SLC proteins transporting carboxylates (SLC13, and SLC16). SLC13A1 represents the subfamily of Na⁺‐dependent sulfate transporters (NaS), while SLC13A5 represents the subfamily of Na⁺‐dependent di‐ and tricarboxylate transporters (NaDC). SLC16A1 is shown as an example of a monocarboxylate transporter (MCT).