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. 2020 Dec 3;60(25):13738–13756. doi: 10.1002/anie.202008150

Scheme 4.

Scheme 4

Detailed optimization of the cross‐metathesis step in the synthesis of Virginiamycin M2 (4). n.r.=no reaction; py=3‐bromopyridine; TBS=tert‐butyldimethylsilyl; TMS=trimethylsilyl.