TABLE 3.
Predischarge echocardiography and in‐hospital and 30‐day clinical outcomes
| SAPIEN 3 Ultran = 141 | SAPIEN 3n = 141 | p value | |
|---|---|---|---|
| Echocardiogram | |||
| Peak aortic velocity, m/s | 2.0 ± 0.38 | 2.0 ± 0.40 | .58 |
| Peak aortic gradient, mmHg | 19.0 ± 6.8 | 17.8 ± 6.9 | .14 |
| Mean aortic gradient, mmHg | 10.3 ± 3.8 | 9.6 ± 3.9 | .14 |
| PVL | |||
| ≥Mild | 10 (7.2) | 31 (22.3) | .002 |
| Moderate or severe | 1 (0.72) | 4 (2.9) | .18 |
| In‐hospital and 30‐day clinical outcomes | |||
| All‐cause mortality | 3 (2.1) | 3 (2.1) | >.90 |
| Stroke or TIA | 2 (1.4) | 2 (1.4) | >.90 |
| Bleeding complication | |||
| Life‐threatening or disabling | 2 (1.4) | 6 (4.3) | .15 |
| Major | 5 (5.7) | 9 (6.4) | .62 |
| Major vascular complication | 7 (4.5) | 16 (11.4) | .05 |
| Hemoglobin drop (before‐after), g/L | 16.2 ± 8,9 | 19.3 ± 13.9 | .03 |
| AKI | 1 (0.7) | 3 (2.1) | .32 |
| Stage 1 | 1 (0.7) | 3 (2.1) | .32 |
| Stage 2 | 0 (0) | 0 (0) | >.90 |
| Stage 3 | 0 (0) | 0 (0) | >.90 |
| Creatinine change (after‐before), μmol/L | −11.8 ± 21.9 | −7.2 ± 22.1 | .08 |
| Creatinine change (after / before) | 0.89 ± 0.11 | 0.93 ± 0.20 | .03 |
| PMI | 8 (5.7) | 7 (5.0) | .80 |
| PMI without prior PMI | 8 (6.3) | 7 (5.6) | .80 |
| PMI with prior first‐degree block | 3 (7.9) | 3 (7.9) | >.90 |
| PMI with prior right bundle branch block | 2 (16.7) | 4 (26.7) | .53 |
| Post PR duration, ms | 199.5 ± 40.4 | 191.0 ± 39.3 | .15 |
| PR duration (after‐before), ms | 8.4 ± 32.5 | 6.0 ± 31.0 | .42 |
| Post QRS duration, ms | 119.7 ± 30.3 | 118.5 ± 33.8 | .77 |
| QRS duration (after‐before), ms | 7.5 ± 21.9 | 6.3 ± 20.5 | .65 |
| New left bundle branch block | 19 (13.7) | 22 (16.7) | .49 |
| LOS, days | 2.7 ± 3.0 | 3.7 ± 4.3 | .017 |
| LOS after TAVR, days | 2.0 ± 2.2 | 2.5 ± 2.5 | .05 |
| Device success | 135 (95.7) | 132 (93.6) | .43 |
| Any device failure requiring reintervention within 30‐days | 0 (0) | 1 (0.71) | .32 |
| 30‐days mortality | 3 (2.1) | 3 (2.1) | >.90 |
Notes: Values are n (%) or mean ± SD.
Abbreviations: AKI, acute kidney injury; LOS, length of hospital stay; PVL, paravalvular leakage; TAVR, transcatheter aortic valve replacement; TIA, transient ischemic attack. Other abbreviations as in Table 1.