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. 2021 Jun 30;18:69. doi: 10.1186/s12954-021-00519-y

Table 4.

Treatment efficacy and adherence to therapy

PWID group Control group p
SVR 12 99 (98%) 172 (98%) N. S.
 Lost to follow-up 2 (2.0%) 1 (0.6%)
 Relapse 0 (0%) 4 (1.4%)
SVR 24 89 (88.1%) 163 (92.1%) N. S.
 Lost to follow-up 10 (9.9%) 5 (2.8%)
 Relapse 1 (1%) 9 (5.1%)
 Reinfection 1 (1%) 0 (0%)
SVR 12 according to adherence N. S.
 100% adherent 69 (100%) 153 (95.6%)
 Non-100% adherent 30 (93.8%) 15 (88.2%)
Treatment termination on time 99 (98%) 169 (95.5%) N. S.
Premature treatment termination 0 (0%) 1 (0.6%) N. S.
Postponed treatment termination 2 (2.0%) 7 (4.0%) N. S.
Delay (days)
 Patient 1 3
 Patient 2 3
 Patient 3 2
 Patient 4 1
 Patient 5 1
 Patient 6 1
 Patient 7 7
 Patient 8 2
 Patient 9 2
Missed doses (no. of patients)
 1 dose 0 3 N. S.
 2 doses 0 3
 3 doses 2 0
 7 doses 0 1
Postponed visits (no. of patients) 29 (28.7%) 7 (4.0%) < 0.001
 1 visit 17 7
 2 visits 8 0
 3 visits 4 0
Missed visits (no. of patients) 13 (12.9%) 6 (3.4%) 0.006
 1 visit 11 6
 2 visits 2 0
Lack of medication (no. of patients) 1 (1%) 2 (1.1%) N. S.
 Patient 1 (missed doses) 3
 Patient 2 (missed doses) 2
 Patient 3 (missed doses) 2
Missed visit 12 weeks post-treatment (SVR 12) 2 (2%) 1 (0.6%) N. S.
Missed visit 24 weeks post-treatment (SVR 24) 11 (10.9%) 2 (1.1%) 0.004

P value of < 0.05 was considered statistically significant and the results are displayed in bold

PWID people who inject drugs group, SVR sustained virological response