Table 4.
Treatment efficacy and adherence to therapy
PWID group | Control group | p | |
---|---|---|---|
SVR 12 | 99 (98%) | 172 (98%) | N. S. |
Lost to follow-up | 2 (2.0%) | 1 (0.6%) | |
Relapse | 0 (0%) | 4 (1.4%) | |
SVR 24 | 89 (88.1%) | 163 (92.1%) | N. S. |
Lost to follow-up | 10 (9.9%) | 5 (2.8%) | |
Relapse | 1 (1%) | 9 (5.1%) | |
Reinfection | 1 (1%) | 0 (0%) | |
SVR 12 according to adherence | N. S. | ||
100% adherent | 69 (100%) | 153 (95.6%) | |
Non-100% adherent | 30 (93.8%) | 15 (88.2%) | |
Treatment termination on time | 99 (98%) | 169 (95.5%) | N. S. |
Premature treatment termination | 0 (0%) | 1 (0.6%) | N. S. |
Postponed treatment termination | 2 (2.0%) | 7 (4.0%) | N. S. |
Delay (days) | |||
Patient 1 | 3 | ||
Patient 2 | 3 | ||
Patient 3 | 2 | ||
Patient 4 | 1 | ||
Patient 5 | 1 | ||
Patient 6 | 1 | ||
Patient 7 | 7 | ||
Patient 8 | 2 | ||
Patient 9 | 2 | ||
Missed doses (no. of patients) | |||
1 dose | 0 | 3 | N. S. |
2 doses | 0 | 3 | |
3 doses | 2 | 0 | |
7 doses | 0 | 1 | |
Postponed visits (no. of patients) | 29 (28.7%) | 7 (4.0%) | < 0.001 |
1 visit | 17 | 7 | |
2 visits | 8 | 0 | |
3 visits | 4 | 0 | |
Missed visits (no. of patients) | 13 (12.9%) | 6 (3.4%) | 0.006 |
1 visit | 11 | 6 | |
2 visits | 2 | 0 | |
Lack of medication (no. of patients) | 1 (1%) | 2 (1.1%) | N. S. |
Patient 1 (missed doses) | 3 | ||
Patient 2 (missed doses) | 2 | ||
Patient 3 (missed doses) | 2 | ||
Missed visit 12 weeks post-treatment (SVR 12) | 2 (2%) | 1 (0.6%) | N. S. |
Missed visit 24 weeks post-treatment (SVR 24) | 11 (10.9%) | 2 (1.1%) | 0.004 |
P value of < 0.05 was considered statistically significant and the results are displayed in bold
PWID people who inject drugs group, SVR sustained virological response