Table 1.
The relationship of FMNL2 and clinicopathological variables in breast cancer tissues
| Variables | Total No. of patients (n = 114) | FMNL2 expression | χ2 | P-value | |
|---|---|---|---|---|---|
| Negative (n = 80) | Positive (n = 34) | ||||
| Age | 1.565 | 0.211 | |||
| < 50 | 65 | 47 | 18 | ||
| ≥ 50 | 49 | 30 | 19 | ||
| histopathological type | 0.814 | 0.665 | |||
| Invasive ductal carcinoma | 111 | 78 | 33 | ||
| Ductal carcinoma in situ | 2 | 1 | 1 | ||
| Invasive lobular carcinoma | 1 | 1 | 0 | ||
| Clinical stage | 5.48 | 0.065 | |||
| 1 | 14 | 12 | 2 | ||
| 2 | 48 | 37 | 11 | ||
| 3 | 52 | 31 | 21 | ||
| TNM phase | 0.329 | 0.567 | |||
| I-II | 65 | 47 | 18 | ||
| III-IV | 49 | 33 | 16 | ||
| Ki67 | 11.668 | 0.001* | |||
| < 14% | 44 | 39 | 5 | ||
| ≥ 14% | 70 | 41 | 29 | ||
| Tumor size | 0.495 | 0.482 | |||
| < 2 cm | 32 | 24 | 8 | ||
| ≥ 2 cm | 82 | 56 | 26 | ||
| ER status | 6.327 | 0.012* | |||
| ER (−) | 29 | 15 | 14 | ||
| ER (+) | 85 | 65 | 20 | ||
| PR status | 2.173 | 0.14 | |||
| PR (−) | 42 | 26 | 16 | ||
| PR (+) | 72 | 54 | 18 | ||
| HER2 status | 0.31 | 0.578 | |||
| HER2 (−) | 36 | 24 | 12 | ||
| HER2 (+) | 78 | 56 | 22 | ||
*P < 0.05 indicates a significant association between the variables