Fig. 2.

APOE4 allelic dosage vs. CVLT-List A trajectories among Whites and African Americans: predictive margins from mixed-effects linear regression model^a. Abbreviations: APOE = Apolipoprotein E; CVLT-List A = California Verbal Learning Test, List A; HANDLS = Healthy Aging in Neighborhoods of Diversity across the Life Span. ^a Model 2B, Table 2, fully adjusted model, stratified by race. Figure shows predictive margins of CVLT-List A scores across time, highlighting the significant difference in slope across APOE4 dosage among Whites only. γ₁₂ refers to the fixed effect of APOE4 dosage on the rate of change in CVLT-List A total score for each racial group. “b” is a standardized measure for the regression coefficient γ₁₂ in model where CVLT-LIST A is entered as standardized z-scores within each racial group. It is interpreted as the SD of outcome change per year increase in follow-up time for each APOE4 dosage change. 1 SD of CVLT-LIST A corresponds to 7.71 change in score, overall