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. 2021 Jun 30;2:71. doi: 10.1186/s43058-021-00173-2

Table 4.

Investigator-identified intervention functions targeting identified barriers and facilitators as defined in the behavior change wheel framework

Intervention functions Potential interventions
Education 1. Clinic to adopt regular TB/TPT health education talks for PLHIV
2. Counselling PLHIV about TB and TPT prior to initiation of 3HP
Persuasion 1. Health workers to help convince PLHIV to take 3HP
2. Leverage once-weekly dosing schedule to convince PLHIV to take 3HP
Training 1. Train health workers on how to use digital adherence technology
Environmental restructuring 1. Reduce waiting time for PLHIV by streamlining DOT clinic visits
Enablement 1. Weekly dosing reminders for PLHIV taking 3HP as SAT
2. Consider using fixed-dose combination pills of 3HP to reduce pill burden
3. Provide emotional support for PLHIV using counselors at the clinic

Abbreviations: 3HP rifapentine-isoniazid combination, TB tuberculosis, PLHIV person/people living with HIV, TPT tuberculosis preventive therapy, DOT directly observed therapy, SAT self-administered therapy