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. 2021 Jun 30;13:135. doi: 10.1186/s13148-021-01115-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Venn diagrams illustrating the degree of overlap and uniqueness for the obtained genes from the three network modules for the double active treatment (Lω vs. PP) and the single active treatment (LP vs. PP, Pω vs. PP) comparisons. In A the number of common genes from the overlap are displayed for each comparison is shown, with corresponding gene names denoted in italics, and selection of related pathways in bold. No relevant pathways were revealed for the shared genes of the LP vs. PP and Pω vs. PP comparisons. In B the number of genes that are unique for each comparison are displayed along with a selection of corresponding related pathways. No pathways of relevance were revealed for the unique genes from the Pω vs. PP comparison. L—Lactobacillus reuteri, ω—ω-3 fatty acids, P—placebo